EFFECT OF 5-BROMODEOXYURIDINE ON MAMMALIAN CHROMOSOMES
نویسندگان
چکیده
منابع مشابه
The cellular effect of 5-bromodeoxyuridine on the mammalian embryo.
It is well known that 5-bromodeoxyuridine (BUdR) when injected into pregnant animals may cause exencephaly, cleft palate, and limb abnormalities. Similarly, it is well established that the drug when added to a culture medium may prevent differentiation of embryonic cell systems without affecting cell division or cell viability. The goal of our experiments was to examine whether the congenital m...
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Sister-chromatid exchanges (SCE) were studied in allium cepa L. meristematic cells at the second and third divisions after BrdUrd-substitution during just the first or during the second and third cycles, respectively. The observed SCE nonreciprocal/reciprocal ratios detected at the third division in both experiments, as well as comparison of the lowest SCE frequency observed per cycle and expre...
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15 صفحه اولthe effect of explicit teaching of metacognitive vocabulary learning strategies on recall and retention of idioms
چکیده ندارد.
15 صفحه اولEffect of 5-bromodeoxyuridine on the appearance of the liver isoenzyme of pyruvate kinase.
Hepatocyte cultures derived from 15-day foetal rats produce the liver form of pyruvate kinase (EC 2.7.1.40) only after 3 days of culture. The appearance of the liver form of the enzyme can be blocked by the addition of 5-bromodeoxyuridine on day 2 of culture, but not by addition on day 3 of culture. The reversibility of the action of 5-bromodeoxyuridine was shown when the inhibitor was added on...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1961
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.47.3.396